Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.5
USERS' SCORE
Good
Based on 16 Reviews
8.1
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin E (as D-alpha tocopheryl succinate)
20.1 mg
134%
Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast-free), sodium selenite)
200 mcg
364%
Top Medical Research Studies
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9.5
We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
Read More
9
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
Most Useful Reviews
9
Boosted immune function
118 people found this helpful
Selenium is an essential trace element that is vital for our body's activity, particularly in immune defence and heart health. However, our modern lifestyle often leads to insufficient intake. I bought this for my mother, and she is thrilled with the improvements in her health. I’ve read it’s great for enhancing female beauty too, which is an added bonus. It’s important to take one capsule daily with food or as directed by your doctor, and this formulation contains all three forms of selenium for optimal benefits.
Read More
9
Increased energy levels
11 people found this helpful
No need for modern medicine! After being diagnosed with Hashimoto's last year, I opted to explore natural remedies instead of relying solely on thyroid medication prescribed by my doctor. Going gluten-free and taking selenium has significantly improved my fatigue. I’ve been using this supplement for almost a year and it has restored my energy. I'm an avid runner, and I've regained my stamina. I felt no withdrawal symptoms after switching from my prescription to selenium, and my latest blood work indicates my health is the best it's been in a decade!
Read More
6
Healthy skin support
28 people found this helpful
In today’s fast-paced world, maintaining a balance of vitamins and minerals has become increasingly challenging. Selenium is vital for good health and acts as an excellent antioxidant, protecting cells from ageing. It also aids skin elasticity, especially when combined with vitamin E, which is particularly beneficial for women. Moreover, selenium strengthens blood vessels and may reduce the risk of plaque formation, thus promoting heart health. Taking care of your wellbeing is paramount; if you find this information useful, please show your support!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 24 Researches
7.5
- All Researches
9.5
We explored a new approach to treat blood clots using piezoelectric selenene. This study introduced a unique design that combines selenene with platelet membranes, enhancing its ability to target thrombosis.
Under ultrasound, the selenene generates reactive oxygen species, effectively dissolving clots without the bleeding risks associated with traditional therapies.
In both lab and live animal tests, these selenium-based nanosheets demonstrated impressive results, outperforming a standard clinical drug. It's a promising step toward safer, more effective treatments for thrombosis.
Under ultrasound, the selenene generates reactive oxygen species, effectively dissolving clots without the bleeding risks associated with traditional therapies.
In both lab and live animal tests, these selenium-based nanosheets demonstrated impressive results, outperforming a standard clinical drug. It's a promising step toward safer, more effective treatments for thrombosis.
Read More
9.5
We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
Read More
9
We explored the effectiveness of a new polymer infused with selenium in tackling blood clots and infections associated with medical devices. This SNAP-Se-1 composite works by releasing nitric oxide (NO), a natural defender against both issues. We found that it remarkably reduced platelet adhesion by 85.5% while also displaying antibacterial properties. Importantly, this innovative approach minimizes the need for traditional antibiotic treatments. Overall, while we see promising results in lab settings, further research is needed to confirm these benefits in real-world applications.
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9
Our exploration focused on how tocotrienols, a form of vitamin E, influence blood clotting, especially in the context of risk factors like stroke. Using a canine model, we assessed the effects of tocotrienols on platelet aggregation and thrombus formation.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
Read More
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
User Reviews
USERS' SCORE
Good
Based on 16 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Boosted immune function
118 people found this helpful
Selenium is an essential trace element that is vital for our body's activity, particularly in immune defence and heart health. However, our modern lifestyle often leads to insufficient intake. I bought this for my mother, and she is thrilled with the improvements in her health. I’ve read it’s great for enhancing female beauty too, which is an added bonus. It’s important to take one capsule daily with food or as directed by your doctor, and this formulation contains all three forms of selenium for optimal benefits.
Read More
9
Increased energy levels
11 people found this helpful
No need for modern medicine! After being diagnosed with Hashimoto's last year, I opted to explore natural remedies instead of relying solely on thyroid medication prescribed by my doctor. Going gluten-free and taking selenium has significantly improved my fatigue. I’ve been using this supplement for almost a year and it has restored my energy. I'm an avid runner, and I've regained my stamina. I felt no withdrawal symptoms after switching from my prescription to selenium, and my latest blood work indicates my health is the best it's been in a decade!
Read More
6
Healthy skin support
28 people found this helpful
In today’s fast-paced world, maintaining a balance of vitamins and minerals has become increasingly challenging. Selenium is vital for good health and acts as an excellent antioxidant, protecting cells from ageing. It also aids skin elasticity, especially when combined with vitamin E, which is particularly beneficial for women. Moreover, selenium strengthens blood vessels and may reduce the risk of plaque formation, thus promoting heart health. Taking care of your wellbeing is paramount; if you find this information useful, please show your support!
Read More
9
Raises selenium levels
10 people found this helpful
This is an excellent selenium supplement! My blood test showed that my selenium levels doubled. I didn't expect this since I didn't take it every day. Take it without hesitation; the effectiveness is undeniable.
Read More
6
Reduced blood clot risk
8 people found this helpful
Vitamin E is critical for its strong antioxidant effects, helping to prevent lipid oxidation, atherosclerosis, and blood clots, while also lowering blood pressure and bad cholesterol. It’s often referred to as the “vitamin of rejuvenation” for its role in preventing age-related diseases. Having turned 50, I began taking it myself, choosing vegetable capsules to avoid additives. Gradually, I’ve noticed my skin feeling more youthful and refreshed.
Read More
Frequently Asked Questions
9
Increased energy levels
11 people found this helpful
No need for modern medicine! After being diagnosed with Hashimoto's last year, I opted to explore natural remedies instead of relying solely on thyroid medication prescribed by my doctor. Going gluten-free and taking selenium has significantly improved my fatigue. I’ve been using this supplement for almost a year and it has restored my energy. I'm an avid runner, and I've regained my stamina. I felt no withdrawal symptoms after switching from my prescription to selenium, and my latest blood work indicates my health is the best it's been in a decade!
6
Personalised response
5 people found this helpful
This drug may be beneficial if it suits you. I took it alongside prescribed AIT treatment. My doctor recommended selecting a medication from the pharmacy or exploring iHerb. After considering prices and compositions, I chose this one. This is my second course of selenium; while the first helped somewhat, this feels better. Each drug interacts differently with our bodies, so finding the right one takes patience. Initially, I monitored my body closely, but after a month of taking it, my condition has notably improved, despite its unpleasant smell!
6
Healthy skin support
28 people found this helpful
In today’s fast-paced world, maintaining a balance of vitamins and minerals has become increasingly challenging. Selenium is vital for good health and acts as an excellent antioxidant, protecting cells from ageing. It also aids skin elasticity, especially when combined with vitamin E, which is particularly beneficial for women. Moreover, selenium strengthens blood vessels and may reduce the risk of plaque formation, thus promoting heart health. Taking care of your wellbeing is paramount; if you find this information useful, please show your support!
6
Supports blood flow
1 people found this helpful
Great high-quality and effective drug! The combination of selenium with vitamin E reduces fatigue, enhances work capacity, and supports the body's defences. Selenium supports the immune system and maintains healthy hair and nails, while vitamin E slows down cell ageing, strengthens vessel walls, positively affects red blood cell stability, and reduces the risk of blood clots.
7.5
Reduces fibrillation incidents
4 people found this helpful
I ordered selenium for my mother's atrial fibrillation, believing it good for the circulatory system and thyroid. Vitamin E enhances blood flow, so I’m pleased with this complex! After starting to take it, my mother's atrial fibrillation seems to occur less often or is milder, which is encouraging. I also suffer from varicose veins in my lower limbs, so I hope for improvement.
7.5
Support for heart health
3 people found this helpful
I trust the renowned American brand Life Extension, which has been dedicated to health research since 1980. They've pioneered many health products, including this selenium complex that comprises three forms of selenium plus vitamin E for enhanced absorption. Selenium is crucial for the heart, brain, and thyroid health, and it can potentially extend life. I’m 55, dealing with several health issues, including hypertension, but since taking this selenium complex under my endocrinologist's guidance, my test results for thyroid hormones have improved, alongside lower blood pressure.
7
Improved haemoglobin levels
5 people found this helpful
My aim was to increase my father’s low haemoglobin levels. He was hospitalised, and during that time, he took selenium from Solgar. It proved effective as his haemoglobin improved remarkably from 65 to 106 within a few months. His health condition has shown significant improvement. Although I can't definitively attribute this solely to selenium, its combination with liquid chlorophyll contributed to his better state.
9
Raises selenium levels
10 people found this helpful
This is an excellent selenium supplement! My blood test showed that my selenium levels doubled. I didn't expect this since I didn't take it every day. Take it without hesitation; the effectiveness is undeniable.
9.5
We explored a new approach to treat blood clots using piezoelectric selenene. This study introduced a unique design that combines selenene with platelet membranes, enhancing its ability to target thrombosis.
Under ultrasound, the selenene generates reactive oxygen species, effectively dissolving clots without the bleeding risks associated with traditional therapies.
In both lab and live animal tests, these selenium-based nanosheets demonstrated impressive results, outperforming a standard clinical drug. It's a promising step toward safer, more effective treatments for thrombosis.
Under ultrasound, the selenene generates reactive oxygen species, effectively dissolving clots without the bleeding risks associated with traditional therapies.
In both lab and live animal tests, these selenium-based nanosheets demonstrated impressive results, outperforming a standard clinical drug. It's a promising step toward safer, more effective treatments for thrombosis.
8
We investigated how selenium-based nanomaterials boost photoacoustic imaging to identify carotid artery blood clots more effectively. By using a thrombosis model in mice, we found that these nanocomposites significantly enhanced imaging signals—up to 5 times greater—which helps diagnose the extent of carotid atherosclerosis.
This research suggests that selenium/polypyrrole nanoparticles may be a promising tool for improving the detection and diagnosis of carotid thrombosis, potentially leading to better stroke prevention strategies.
This research suggests that selenium/polypyrrole nanoparticles may be a promising tool for improving the detection and diagnosis of carotid thrombosis, potentially leading to better stroke prevention strategies.
7
We explored how low-dose antioxidant supplements affect urinary markers linked to blood clotting and cardiovascular health. In this randomized, double-blind, placebo-controlled study with 186 healthy volunteers, one group received supplements while the other received a placebo for two years.
Our findings show that participants who took the multi-antioxidants had significantly lower levels of a specific urinary marker associated with platelet activity. Notably, selenium was particularly linked to these results, suggesting it can help reduce clot formation, which might support heart health.
Our findings show that participants who took the multi-antioxidants had significantly lower levels of a specific urinary marker associated with platelet activity. Notably, selenium was particularly linked to these results, suggesting it can help reduce clot formation, which might support heart health.
9.5
We explored the effects of ebselen, a selenium compound known for its antioxidant properties, on blood clot formation in rats. Our study demonstrated that ebselen significantly delayed thrombus formation in microvessels.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
In particular, animals treated with ebselen showed a marked delay in vessel occlusion compared to those treated with a control substance. In most cases, ebselen entirely prevented blood clot formation in arterioles.
This suggests that ebselen can be effective in reducing the risk of blood clots, particularly in situations characterized by oxidative stress.
References
- Hu H, Xia L, Wang J, Huang X, Zhao Q, et al. Bionanoengineered 2D monoelemental selenene for piezothrombolysis. Biomaterials. 2024;305:122468. 10.1016/j.biomaterials.2024.122468
- He F, Hou W, Lan Y, Gao W, Zhou M, et al. High Contrast Detection of Carotid Neothrombus with Strong Near-Infrared Absorption Selenium Nanosphere Enhanced Photoacoustic Imaging. Int J Nanomedicine. 2023;18:4043. 10.2147/IJN.S404743
- Mondal A, Douglass M, Hopkins SP, Singha P, Tran M, et al. Multifunctional Nitroso--acetylpenicillamine-Incorporated Medical-Grade Polymer with Selenium Interface for Biomedical Applications. ACS Appl Mater Interfaces. 2019;11:34652. 10.1021/acsami.9b10610
- Arnaud J, Bost M, Vitoux D, Labarère J, Galan P, et al. Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites. J Am Coll Nutr. 2007;26:405.
- Lindenblatt N, Schareck W, Belusa L, Nickels RM, Menger MD, et al. Anti-oxidant ebselen delays microvascular thrombus formation in the rat cremaster muscle by inhibiting platelet P-selectin expression. Thromb Haemost. 2003;90:882.
- Ricetti MM, Guidi GC, Tecchio C, Bellisola G, Rigo A, et al. Effects of sodium selenite on in vitro interactions between platelets and endothelial cells. Int J Clin Lab Res. 1999;29:80.
- Vitoux D, Chappuis P, Arnaud J, Bost M, Accominotti M, et al. [Selenium, glutathione peroxidase, peroxides and platelet functions]. Ann Biol Clin (Paris). 1996;54:181.
- Herrick AL, Rieley F, Schofield D, Hollis S, Braganza JM, et al. Micronutrient antioxidant status in patients with primary Raynaud's phenomenon and systemic sclerosis. J Rheumatol. 1994;21:1477.
- Perona G, Schiavon R, Guidi GC, Veneri D, Minuz P. Selenium dependent glutathione peroxidase: a physiological regulatory system for platelet function. Thromb Haemost. 1990;64:312.
- Jafar Haeri SM, Dashti G, Mardani M, Rashidi B, Nikgoftar Fathi A, et al. Effect of Vitamin E on Apoptosis of the Endothelial Cells of the Carotid Arteries in Hypercholesterolemic Male Rabbits. ARYA Atheroscler. 2023;19:10. 10.48305/arya.2022.39175.2824
- Ho JI, Ng EY, Chiew Y, Koay YY, Chuar PF, et al. The effects of vitamin E on non-proliferative diabetic retinopathy in type 2 diabetes mellitus: Are they sustainable with 12 months of therapy. SAGE Open Med. 2022;10:20503121221095324. 10.1177/20503121221095324
- Ceran C, Aksam E, Aksam B, Yenidünya S, Suludere Z, et al. Tamoxifen-Related Thrombosis: An Experimental Study in Rat Venous Microvascular Anastomosis Model. Ann Plast Surg. 2017;78:213. 10.1097/SAP.0000000000000798
- Pastori D, Carnevale R, Cangemi R, Saliola M, Nocella C, et al. Vitamin E serum levels and bleeding risk in patients receiving oral anticoagulant therapy: a retrospective cohort study. J Am Heart Assoc. 2013;2:e000364. 10.1161/JAHA.113.000364
- Sasaki Y, Kobara N, Higashino S, Giddings JC, Yamamoto J. Astaxanthin inhibits thrombosis in cerebral vessels of stroke-prone spontaneously hypertensive rats. Nutr Res. 2011;31:784. 10.1016/j.nutres.2011.09.010
- Fahim MA, Nemmar A, Singh S, Hassan MY. Antioxidants alleviate nicotine-induced platelet aggregation in cerebral arterioles of mice in vivo. Physiol Res. 2011;60:695.
- Qureshi AA, Karpen CW, Qureshi N, Papasian CJ, Morrison DC, et al. Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries. Lipids Health Dis. 2011;10:58. 10.1186/1476-511X-10-58
- Ristow B. Preoperative use of alpha tocopherol does not increase the risk of hematoma in the face lift patient: a preliminary report. Plast Reconstr Surg. 2009;124:1696. 10.1097/PRS.0b013e3181b98a3a
- Ping-Chia L, I-Ju L, Yu-Ching L, Li-Ching C, Wen-Chung C. Substance P scavenger enhances antioxidant defenses and prevents prothrombotic effects on the rat lung after acute exposure to oil smoke. J Biomed Sci. 2009;16:58. 10.1186/1423-0127-16-58
- Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE. Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study. Circulation. 2007;116:1497.
- Singh I, Turner AH, Sinclair AJ, Li D, Hawley JA. Effects of gamma-tocopherol supplementation on thrombotic risk factors. Asia Pac J Clin Nutr. 2007;16:422.
- Allman-Farinelli MA, Dawson B. Diet and aging: bearing on thrombosis and hemostasis. Semin Thromb Hemost. 2005;31:111.
- Noguchi T, Ikeda K, Sasaki Y, Yamamoto J, Yamori Y. Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2004;31 Suppl 2:S24.
- Miyamoto S, Kawano H, Takazoe K, Soejima H, Sakamoto T, et al. Vitamin E improves fibrinolytic activity in patients with coronary spastic angina. Thromb Res. 2004;113:345.
- Lindenblatt N, Bordel R, Schareck W, Menger MD, Vollmar B. Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo. Arterioscler Thromb Vasc Biol. 2004;24:601.
